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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 2
1978 3
1979 1
1980 4
1981 1
1982 2
1983 3
1984 7
1985 9
1986 9
1987 16
1988 21
1989 13
1990 21
1991 23
1992 22
1993 23
1994 37
1995 31
1996 37
1997 41
1998 31
1999 38
2000 55
2001 46
2002 62
2003 51
2004 55
2005 54
2006 60
2007 50
2008 63
2009 60
2010 63
2011 56
2012 75
2013 76
2014 65
2015 71
2016 64
2017 58
2018 64
2019 69
2020 75
2021 98
2022 96
2023 93
2024 49

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1,859 results

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Page 1
Lysosomal acidification mechanisms.
Mindell JA. Mindell JA. Annu Rev Physiol. 2012;74:69-86. doi: 10.1146/annurev-physiol-012110-142317. Annu Rev Physiol. 2012. PMID: 22335796 Review.
Because this activity separates electric charge and generates a transmembrane voltage, another ion must move to dissipate this voltage for net pumping to occur. ...Exciting new results suggest that lysosomal pH may be dynamically regulated in some cell types. …
Because this activity separates electric charge and generates a transmembrane voltage, another ion must move to dissipate this vol …
Role of ion channels in gastrointestinal cancer.
Anderson KJ, Cormier RT, Scott PM. Anderson KJ, et al. World J Gastroenterol. 2019 Oct 14;25(38):5732-5772. doi: 10.3748/wjg.v25.i38.5732. World J Gastroenterol. 2019. PMID: 31636470 Free PMC article. Review.
Ca(2+) is a ubiquitous second messenger, serving as a signaling molecule for a variety of cellular processes such as control of the cell cycle, apoptosis, and migration. Various members of the TRP superfamily, including TRPM8, TRPM7, TRPM6 and TRPM2, have been implicated i …
Ca(2+) is a ubiquitous second messenger, serving as a signaling molecule for a variety of cellular processes such as control of the c …
KCNQs: Ligand- and Voltage-Gated Potassium Channels.
Abbott GW. Abbott GW. Front Physiol. 2020 Jun 23;11:583. doi: 10.3389/fphys.2020.00583. eCollection 2020. Front Physiol. 2020. PMID: 32655402 Free PMC article. Review.
Voltage-gated potassium (Kv) channels in the KCNQ (Kv7) family are essential features of a broad range of excitable and non-excitable cell types and are found in organisms ranging from Hydra vulgaris to Homo sapiens. Although they are firmly in the superfamil …
Voltage-gated potassium (Kv) channels in the KCNQ (Kv7) family are essential features of a broad range of excitable and non-ex …
Molecular Mechanisms of Renal Magnesium Reabsorption.
Ellison DH, Maeoka Y, McCormick JA. Ellison DH, et al. J Am Soc Nephrol. 2021 Sep;32(9):2125-2136. doi: 10.1681/ASN.2021010042. Epub 2021 May 27. J Am Soc Nephrol. 2021. PMID: 34045316 Free PMC article. Review.
The kidney plays a central role in maintaining serum magnesium within a narrow range (0.70-1.10 mmol/L). Along the proximal tubule and thick ascending limb, magnesium reabsorption occurs via paracellular pathways. Members of the claudin family form the magnesium pores in t …
The kidney plays a central role in maintaining serum magnesium within a narrow range (0.70-1.10 mmol/L). Along the proximal tubule an …
Bioelectric Properties of Myogenic Progenitor Cells.
Fennelly C, Soker S. Fennelly C, et al. Bioelectricity. 2019 Mar 1;1(1):35-45. doi: 10.1089/bioe.2018.0002. Epub 2019 Mar 18. Bioelectricity. 2019. PMID: 34471807 Free PMC article. Review.
Modern stem cell research has mainly focused on protein expression and transcriptional networks. However, transmembrane voltage gradients generated by ion channels and transporters have demonstrated to be powerful regulators of cellular processes. These physiologica …
Modern stem cell research has mainly focused on protein expression and transcriptional networks. However, transmembrane voltage gradi …
Ca2+-dependent modulation of voltage-gated myocyte sodium channels.
Salvage SC, Habib ZF, Matthews HR, Jackson AP, Huang CL. Salvage SC, et al. Biochem Soc Trans. 2021 Nov 1;49(5):1941-1961. doi: 10.1042/BST20200604. Biochem Soc Trans. 2021. PMID: 34643236 Free PMC article. Review.
Voltage-dependent Na+ channel activation underlies action potential generation fundamental to cellular excitability. ...Interventions increasing cytoplasmic [Ca2+]i down-regulated Imax leaving V1/2 constant in native loose patch clamped, wild-type murine skeletal an …
Voltage-dependent Na+ channel activation underlies action potential generation fundamental to cellular excitability. ...Interventions …
Signal transduction in photoreceptor histidine kinases.
Möglich A. Möglich A. Protein Sci. 2019 Nov;28(11):1923-1946. doi: 10.1002/pro.3705. Epub 2019 Aug 20. Protein Sci. 2019. PMID: 31397927 Free PMC article. Review.
Photoreceptor histidine kinases are a subset of mostly soluble, cytosolic SHKs that sense light in the near-ultraviolet to near-infrared spectral range. Owing to their experimental tractability, photoreceptor histidine kinases serve as paradigms and provide unusually detai …
Photoreceptor histidine kinases are a subset of mostly soluble, cytosolic SHKs that sense light in the near-ultraviolet to near-infrared spe …
AHNAK: The quiet giant in calcium homeostasis.
Sundararaj S, Ravindran A, Casarotto MG. Sundararaj S, et al. Cell Calcium. 2021 Jun;96:102403. doi: 10.1016/j.ceca.2021.102403. Epub 2021 Mar 27. Cell Calcium. 2021. PMID: 33813182 Review.
This enables AHNAK to participate in various multi-protein complexes thereby orchestrating a range of diverse biological processes, including tumour suppression, immune regulation and cell architecture maintenance. ...In this article we review and examine recent adv …
This enables AHNAK to participate in various multi-protein complexes thereby orchestrating a range of diverse biological processes, i …
Lysosomal Ion Channels: What Are They Good For and Are They Druggable Targets?
Riederer E, Cang C, Ren D. Riederer E, et al. Annu Rev Pharmacol Toxicol. 2023 Jan 20;63:19-41. doi: 10.1146/annurev-pharmtox-051921-013755. Epub 2022 Sep 23. Annu Rev Pharmacol Toxicol. 2023. PMID: 36151054 Free article. Review.
Lysosomes play fundamental roles in material digestion, cellular clearance, recycling, exocytosis, wound repair, Ca(2+) signaling, nutrient signaling, and gene expression regulation. The organelle also serves as a hub for important signaling networks involving the mTOR and …
Lysosomes play fundamental roles in material digestion, cellular clearance, recycling, exocytosis, wound repair, Ca(2+) signaling, nutrient …
Voltage-gated potassium channels as therapeutic targets.
Wulff H, Castle NA, Pardo LA. Wulff H, et al. Nat Rev Drug Discov. 2009 Dec;8(12):982-1001. doi: 10.1038/nrd2983. Nat Rev Drug Discov. 2009. PMID: 19949402 Free PMC article. Review.
The human genome encodes 40 voltage-gated K(+) channels (K(V)), which are involved in diverse physiological processes ranging from repolarization of neuronal and cardiac action potentials, to regulating Ca(2+) signalling and cell volume, to driving cellular p …
The human genome encodes 40 voltage-gated K(+) channels (K(V)), which are involved in diverse physiological processes ranging …
1,859 results